<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, A21T, V31I, M50I, I60V, I72V, L101I, T112V, T124A, G134N, D167E, G193E, V201I, I208L, L234I, D256E, D270N S283G
>LBTB084| codons 1-288
FLDGIDKAQEDHEKYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGV
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSATVKAACWWANIKQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGEYSAGERIIDIIATDLQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRNYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10M, I13V, G16E, K20R, E35D, M36I, P39A, R41K, I62V, L63T, E65D, K70R, L89M  
>LBTB084| codons 1-99
PQITLWQRPMVTVKIEGQLREALLDTGADDTVLEDINLAGKWKPKMIGGIGGFIKVRQYD
QVTIDICGHRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39N, V60I, T107S, D123E, I142V, A158S, S162A, K173A, D177E, Q207D, R211K, V245Q, E248D, A272P, K281R, T286A, E291D, V292I, I293V, P294T, E297K, E312D, D324E, R356K, M357K, G359S, A360T, K366R, A371V, I375V, A376V, K390R, E399D, A400T, V435A, F440Y, T450S, V466I, V467I, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, A534S, V548I, A554S  
>LBTB084| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVSVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPSIFQASMTKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVTLTKEAE
LELAENREILKDPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKKRST
HTNDVRQLTEVVQKVVTESIVIWGKTPKFRLPIQKETWDTWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETYYVDGAANRESKLGKAGYVTDRGRQKIISLTDTTNQKTELH
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKEKVYLSWVPAHK
GIGGNEQIDKLVSSGIRKVL

References
Author Title Citation
Vidal, N Genetic characterization of eight full-length HIV type 1 genomes from the Democratic Republic of Congo (DRC) reveal a new subsubtype, A5, in the A radiation that predominates in the recombinant structure of CRF26_A5U. ARHR, 2009