<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, V31I, M50I, I60V, I72V, Q95S, L101I, T112V, G134S, K136Q, D167E, T218L, I220V, L234I, V260I, A265V V225A, S283G
>KFE267| codons 1-288
FLDGIDKAQEDHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGV
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGSETAYFILKLAGRWPVKVIHTDNGSN
FTSTTVKAACWWASIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQILKVQNFRAYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVIPRRKVKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G16E, K20R, E35D, M36I, P39A, R41K, I62V, L63T, E65D, H69K, V82I, L89M  
>KFE267| codons 1-99
PQITLWQRPLVTVKIEGQLREALLDTGADDTVLEDINLAGKWKPKMIGGIGGFIKVRQYD
QVTIDICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39N, V60I, K64R, I135T, E138A, Q145H, K173S, D177E, Q207A, V245Q, E248D, D250E, A272P, K281R, T286A, E291D, V292I, I293V, P294T, E297K, E312D, Q334H, G335D, R356K, G359T, T377I, K390R, A400T, E404D, L452I, V466I, D471E, L491S, S519N, K530R, A534S, A554N S48C, F77C, F116L
>KFE267| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKICKIGPENPYNTPI
FAIRKKDSTKWRKLVDCRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYLSVPL
DKDFRKYTAFTIPSTNNATPGIRYHYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVTLTKEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIAIESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKIGKAGYVTDRGRQKIVSLTETTNQKTELQ
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK
GIGGNEQVDKLVSNGIRKVL

References
Author Title Citation
Vidal, N Genetic characterization of eight full-length HIV type 1 genomes from the Democratic Republic of Congo (DRC) reveal a new subsubtype, A5, in the A radiation that predominates in the recombinant structure of CRF26_A5U. ARHR, 2009