<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, A21T, I60M, I72V, L74I, T112V, I113V, T124A, T125A, V126F, G134N, I135V, K136Q, K173R, V176L, V201I, L234I S283G
>CY106| codons 1-288
FLDGIDKAQEEHERYHSNWRTMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGM
WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN
FTSAAFKAACWWANVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLRTALQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V32E I13V, K14E, G16E, K20R, E35D, M36I, K45R, R57K, L63S, H69K, L89M  
>CY106| codons 1-99
PQITLWQRPLVTVEIEGQLREALLDTGADDTELEDINLPGRWKPRMIGGIGGFIKVKQYD
QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, V60I, K122E, D123S, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245K, D250E, A272P, K281R, T286A, E291D, V292I, I293V, P294T, G335D, P345S, M357K, G359S, T369A, A371V, I375V, T377M, K388N, A400T, T403R, E404D, K431T, E432D, V435I, D471E, Q480H, L491S, E516D, S519N, Q524M, K527G, E529D, A534S, I556V, V559I  
>CY106| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIII
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQESFKNLKTGKYARKRSA
HTNDVKQLAEVVQKVAMESIVIWGKTPNFKLPIQKETWETWWRDYWQATWIPEWEFVNTP
PLVKLWYQLETDPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESDLVNQIIEMLIGKDKVYLSWVPAHK
GIGGNEQVDKLVSAGVRKIL

References
Author Title Citation
Kousiappa, I Near full-length genetic analysis of HIV sequences derived from Cyprus: evidence of a highly polyphyletic and evolving infection. ARHR, 2009