<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
J11456 J11456 Saudi Arabia 2004 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, S57G, I72V, E96D, L101I, T112V, T124A, T125V, G134N, I135V, K136T, E157Q, V201I, T206S, D232E, L234I, D256E S283G
>J11456| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCGPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQDTAYFILKLAGRWPVKVIHTDNGSN
FTSAVVKAACWWANVTQEFGIPYNPQSQGVVESMNKQLKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSREPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35Q, M36I, R41K, C67E, H69K, V82I, L89M  
>J11456| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVRQYD
QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11R, V35T, V60I, K122E, D123S, I135K, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248N, D250E, A272P, K281R, T286A, E291D, V292I, I293V, S322T, I326V, G335GD, R356K, M357KR, G359S, A371V, A376S, S379G, K390R, T403M, E432D, L452I, R461K, K465R, S468N, D471E, T477A, Q480H, H483Y, D488E, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
>J11456| codons 1-560
PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLTEVVQKISTEGIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKIGKAGYVTDKGRQRVVNLTETTNQKAELH
AIYLALQESGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Yamaguchi, J Identification of new CRF43_02G and CRF25_cpx in Saudi Arabia based on full genome sequence analysis of six HIV type 1 isolates. ARHR, 2008