<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, S39C, L101I, T112V, S119P, T122I, T124A, T125A, D167E, V201I, T206S, T218I, L234I S283G
>J11451| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPVVAKEIVACCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGPN
FISAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I13V, L19I, K20I, M36I, N37S, R41K, I64M, C67GS, H69K, V82I, L89M  
>J11451| codons 1-99
PQITLWQRPLVAVKIGGQIIEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD
QILMEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K22R, V35T, T39N, V60I, K122E, D123N, I135L, K173A, Q174K, T200A, Q207E, R211RK, V245K, K249KQ, A272P, K281R, E291D, V292I, I293V, E312N, D324E, I329V, G335D, F346HY, M357R, R358G, G359S, A376S, T386I, K390R, A400T, E404D, E432D, V435A, K454R, D471E, Q480H, L491S, L517I, S519N, A534S, A554KR  
>J11451| codons 1-560
PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEQDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDIVPLTEEAE
LELAENREILKNPVHGVYYDPSKELIAEVQKQGQDQWTYQIYQEPYKNLKTGKYARRGSA
HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGRAGYVTDRGRQKVVSLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKEKVYLSWVPAHK
GIGGNEQVDKLVSRGIRKVL

References
Author Title Citation
Yamaguchi, J Identification of new CRF43_02G and CRF25_cpx in Saudi Arabia based on full genome sequence analysis of six HIV type 1 isolates. ARHR, 2008