<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I13V, L19I, K20I, M36I, N37S, R41K, L63S, I64M, C67E, H69K, K70R, V82I, L89M  
>J11233| codons 1-99
PQITLWQRPLVSVKIGGQIIEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD
QISMEIEGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39N, E40D, V60I, K104R, I135L, S162G, K173A, Q174K, D177E, T200A, Q207E, R211K, V245E, A272P, K275Q, E291D, V292I, I293V, E297A, E312N, D320E, D324E, I329V, F346G, M357R, R358G, G359S, T377I, K390R, A400T, E404D, E432D, V435I, N447NS, L452LV, R461K, D471E, Q480H, L491P, L517I, S519N, K530KR, A534S, A554N  
>J11233| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQGSMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLLRGTKALTDIVPLTAEAE
LELAENREILKNPVHGVYYEPSKELIAEVQKQGQGQWTYQIYQEPGKNLKTGKYARRGSA
HTNDVKQLTEAVQKIAIESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAASRETKVGKAGYVTDKGRQKVVSLTETTNQKTELH
AIHLALQDSGPEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKERVYLSWVPAHK
GIGGNEQVDKLVSNGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, S17N, L28I, S39C, L45V, M50I, I72IV, L101I, T112V, S119P, T124A, T125A, D167E, V201I, T206S, T218I, L234I, D256E S283G
>J11233| codons 1-288
FLDGIDKAQEEHERYHNNWRAMASDFNIPPVVAKEIVACCDKCQVKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGPN
FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Yamaguchi, J Identification of new CRF43_02G and CRF25_cpx in Saudi Arabia based on full genome sequence analysis of six HIV type 1 isolates. ARHR, 2008