<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, M275V S283G, Q285P
>00PTHSM5| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKIIHTDNGSN
FTSAAVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK
LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQVAGDDCVAGRPDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S   I13V, K20I, E35N, M36I, R41K, H69K, V82I, L89M  
>00PTHSM5| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRSMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, T215Y K219E, N348I K103N   V35T, T39A, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200E, E203K, Q207E, R211S, L228H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V, Q334P, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, Q394R, A400V, E404D, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, I482V, H483Q, L484I, L491S, K512R, E516A, S519N, A534S, A554S  
>00PTHSM5| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI
YQYMDDLYVGSDLEIGQHREKIKELREHLLSWGFYTPDEKHQKEPPFHWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKELIAEVQKQGPDQWTYQIYQEPYKILKTGKYAKRGSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFKLPIRKETWEVWWTDYWQATWIPDWEFVNTP
PLVKLWYRLETEPIAGAETYYVDGAANRETKLGKAGYVTDKGKQKIITLTETTNQKAELQ
AVQIALQDSGSEVNIVTDSQYALGIIQAQPDRSESALVNQIIEQLIKKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Bartolo, I Origin and epidemiological history of HIV-1 CRF14_BG. PLoS One, 2011