Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6792 | CA17080 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 104 |
| 2 | 3TC+D4T+IDV | 57 |
| 3 | D4T+EFV+RTV+SQV | 17 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, V82A | M36I, L63P, A71V, I93L |
| >CA17080| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEINLPGRWKPKIIGGIGGFIKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K103N | T39TA, K64KR, K122E, I135V, I142V, Y232H, A272S, K277R, Q278E, I293V, E297K | R72RG, E302E* |
| >CA16834| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIRKKDSTKWGKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGHELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRELCKLLRGTKALTEVVPLTKEAE L*L |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: Classification, amino acid mutation patterns, and prevalence in a northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive value of HIV-1 genotypic resistance test interpretation algorithms. | J Infect Dis, 2009 |