Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6791 | CA17079 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+AZT+IDV | 78 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S, L90M | L10F | I15V, K20T, E35D, M36I, R41K, R57K, I62V, L63P, I64IL, I66IV, A71T, I93L |
| >CA17079| codons 1-99 PQITLWQRPFVTIKVGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QVPLEVCGHKTIGTVLVGPTPVNIIGRSLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115F, Q151M | A62V, V75I, F77L, F116Y, T215TS | Y181C | E40K, K46Q, K49R, I50V, T58N, S68G, K122E, Q174K, T200A, Q207E, R211K, K219T, V245T, E248D, D250E, S251D, A272P, K277R, T286A, A288S, V292I, E297K | M230MV |
| >CA16833| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTKMEKEGQISRVGPENPYNNPV FVIKKKDGTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFYSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKKNPDIVI CQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFSTPDTKHQKEPPFLWVGYELHPDKWT VQPITLPDKEDWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKSLTEIIPLTKEAE LEL |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |