Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6883 | CA17061 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 61 |
| 2 | 3TC+AZT+IDV | 35 |
| 3 | 3TC+AZT+NFV | 78 |
| 4 | D4T+DDI+EFV | 41 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10LF, N88D | K14R, I15V, E34D, M36I, N37D, R57K, L63C, A71V |
| >CA17061| codons 1-99 PQITLWQRPFVTIRVGGQLKEALLDTGADNTVLDEIDLPGRWKPKMIGGIGGFIKVKQYD QICIEICGHKVIGTVLVGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | K103N | V108VI | T39TA, K49R, V60I, S68SG, K122E, I135T, V189VI, Q207E, R211K, K223KT, V245M, E248D, A288S, I293V, T296S | K281KE |
| >CA16960| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISRIGPENPYNTPI FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYIGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQTEPPFLWMGYELHPDKWT VQPIMLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCELLRGTKSLTEVVPLSEEAE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |