Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6876 | CA17057 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 52 |
| 2 | DDI | 34 |
| 3 | D4T+DDI+IDV | 47 |
| 4 | 3TC+D4T+NFV | 167 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, L90M | G73S | L10I, I13IV, Q18H, K20X, R57K, L63P, K70KR, A71V, V77I |
| >CA17057| codons 1-99 PQITLWQRPIVTVKIGGHLXEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QIPIEICGHRVISTVLIGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K20KR, K22KN, K43Q, V118I, K122E, S134SG, I135IR, I142V, E169D, H208Y, R211K, D218E, Q242QE, K277R, T286A, E297Q, A304G |
| >CA16949| codons 1-304 PISPIETVPVKLKPGMDGPRVNQWPLTEEKIKALVEICTELEQEGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPGRNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTPEKKHQKEPPFLWMGYELHPDKWT VEPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVIPLTQEAE LELG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |