Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6868 | CA17045 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 48 |
| 2 | 3TC+AZT+IDV | 87 |
| 3 | 3TC+D4T+RTV | 39 |
| 4 | D4T+DDC+NFV | 48 |
| 5 | DDI+ 3TC+ EFV | 5 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A, L90M | K43T | L10I, I15V, L19V, E34Q, M36I, G51A, I62V, L63P, A71V, Q92R |
| >CA17045| codons 1-99 PQITLWQRPIVTIKVGGQVKEALLDTGADDTVLQEINLPGRWTPKMIGGIAGFIKVRQYD QVPIEICGHKVIGTVLVGPTPANIIGRNLMTRIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L210W, T215FY | K219E | K20R, V35L, T39A, E53D, V118I, K122E, E138A, S162C, F171Y, G196E, T200A, R211K, E248Q, A272P, L283I, R284K, I293V, E297K | K281KE, A299AG |
| >CA16939| codons 1-303 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICAELEKEGKISKIGPDNPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPYRKQNPDIVI YQYMDDLYVGSDLEIEQHRAKIEELRQHLWKWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPQKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCELIKGTKALTEVVPLTKEGE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |