<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA6866 CA17043 U.S. 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 5
2 DDI 119
3 AZT+ DDI 50
4 DDI+ 3TC+ IDV 112
5 Unknown 87

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82T, L90M   L10LI, K43KN, I62V, L63P, I93L, C95CS  
>CA17043| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWNPKMIGGIGGFIKVRQYD
QVPIEICGHKAIGTVLVGPTPTNIIGRNLMTQLGSTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M, M184V A62V K103N V108I K122E, T131TP, K166R, F214L, A272P, K277R, K281R, T286A, I293V, E297A I270IL
>CA16936| codons 1-303
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DEDFRKYTAFPIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTRILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQLYPGIKVRQLCRLLRGAKALTEVVPLTAEAE
LEL

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005