Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4416 | CA17027 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ NFV+ D4T | 73 |
| 2 | ABC+ SQV+ 3TC+ AZT+ RTV | 15 |
| 3 | ABC+ 3TC+ AZT | 6 |
| 4 | IDV+ ABC+ AZT+ 3TC | 24 |
| 5 | Unknown | 11 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | G73T | L19I, N37T, G51A, L63Q, I64V, A71AV, V77I |
| >CA17027| codons 1-99 PQITLWQRPLVTIKIGGQIKEALLDTGADDTVLEEMTLPGRWKPKIIGGIAGFIKVRQYD QIQVEICGHKVITTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215FV | K219Q | Y181YC, G190GA | V35M, V60I, R83K, E169D, Q207E | D17DA |
| >CA16920| codons 1-250 PISPIETVPVKLKPGMAGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI CQYVDDLYVASDLEIGQHRTKIEELREHLLRWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKD |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |