<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NVP 1
2 None 155
3 3TC+D4T+NVP 48

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR, M184V   Y181C   K20R, V35T, T39N, E40D, K49KR, T69N, I135IT, A158S, K173S, T200A, Q207A, R211K, H221HY, L228LR, V245Q, D250E, S251H, A272P, T286A, E291D, V292I, I293V, P294A, K311R, E312D  
>519810-R| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICNDMEKEGKISRIGPENPYNTPV
FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRSQNPDIVI
CQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKYQKEPPFRWMGYELHPDKWT
VQPIQLPEKEHWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVALTEEAE
LELAENREILRDPVHGVYYDPSKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, M36I, P39Q, R41K, L63P, H69K, L89M  
>519810-R| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEINLQGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Towler, WI Analysis of drug resistance in children receiving antiretroviral therapy for treatment of HIV-1 infection in Uganda. ARHR, 2010