<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 48

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89M  
>393250-S| codons 1-99
PQITLWQRPVVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD
QIAIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N V108I V35T, T39L, E44D, V60I, S68G, T69N, V118I, K122E, D123S, I135T, T139TK, K166R, F171Y, K173A, Q174K, D177E, V179I, T200A, Q207E, R211K, F214L, V245E, E248D, D250E, K277R, T286A, E291D, V292I, I293V, P294T, E312D  
>393250-S| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKDGKISKIGPENPYNTPI
FAIKKKDGNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSIPL
DESFRKYTAFTIPSTNNEKPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPYRAKNPEIII
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPDKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ

References
Author Title Citation
Towler, WI Analysis of drug resistance in children receiving antiretroviral therapy for treatment of HIV-1 infection in Uganda. ARHR, 2010