Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6834 | CA17006 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+3TC+SQV | 108 |
| 2 | 3TC+D4T+IDV | 177 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, L90M | L33LI | L10I, K20I, M36I, I62V, L63P, C67CF, A71V, I85V, I93L |
| >CA17006| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVIEEINLPGRWKPKIIGGIGGFIKVRQYD QVPIEIFGHKVIGTVVVGPTPVNIVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219KN | K22KN, K43KQ, E44ED, T69TA, V118I, K122E, D123DN, T200A, H208Y, R211K, L228LH, V245E |
| >CA16897| codons 1-276 PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV FAIKKKNSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELRQYLWKWGFYTPDNKHQKEPPFHWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKV |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |