<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 48

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V   Y181C   P14L, K32E, V35T, E36A, T39EK, K102R, K122E, I132L, I135R, K173T, D177E, T200A, I202V, Q207D, R211K, V245E, D250E, A272P, I274V, Q278H, L282C, L283I, I293V, K311R  
>389500-E| codons 1-334
PISPIETVPVKLKLGMDGPKVKQWPLTEEKIEALTAICKEMEKEGKISKIGPENPYNTPV
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTLPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI
CQYVDDLYVGSDLEIGQHRAKVEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGVKVKHLCKCIRGTKALTEVVPLTEEAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19V, M36I, N37S, R41K, K45R, H69K, T74S, L89M, I93L R87RK
>389500-E| codons 1-99
PQITLWQRPLVTIKVGGQVKEALLDTGADDTVLEEISLPGKWKPRMIGGIGGFIKVRQYD
QILIEICGKKAIGSVLVGPTPVNIIGKNMLTQLGCTLNF

References
Author Title Citation
Towler, WI Analysis of drug resistance in children receiving antiretroviral therapy for treatment of HIV-1 infection in Uganda. ARHR, 2010