<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L   I13V, K20KR, M36I, R41K, I62V, L63LP, I64V  
>HIV271p| codons 1-99
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEEINLPGKWKPKLIGGIGGFIKVRQYD
QVPVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        S48T, K49KR, I50IV, K122KE, D123E, I135T, S162C, E169EG, D177E, T200I, E248D, A272P, K277R, I293V, P294T, E297A, S322A  
>HIV271p| codons 1-339
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKITRVGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILGPFRKQNPEIVI
YQYMDDLYVGSDLEIGQHRIKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVTLTAEAE
LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQGQWTY

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    I72IV, L101I, K103KR, S119ST, T124A, G193E, V201I, T218S, I220L, I251L, S255T, D279G  
>HIV271p| codons 22-288
MASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVAS
GYIEAEVIPAETGQETAYFILRLAGRWPVKTIHTDNGTNFTSATVKAACWWAGIKQEFGI
PYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGEYSAGERII
DIIATDIQTKELQKQISKLQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVLQDNTDIKVVP
RRKAKIIRDYGKQMAGDGCVASRQDED

References
Author Title Citation
Rangel, HR Absence of primary integrase resistance mutations in HIV type 1-infected patients in Venezuela. ARHR, 2010