<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|RTI NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    A23V, I72IV, L101I, K111KR, M154L, Y194C, T218S, D253E I204IK
>HIV270p| codons 22-288
MVSDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVAS
GYIEAEVIPAETGQETAYFILKLAGRWPVRTIHTDNGSNFTSTTVKAACWWAGIKQEFGI
PYNPQSQGVVESLNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGCSAGERIV
DIKATDIQTKELQKQISKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQENSDIKVVP
RRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84V, L90M L10F, L33IV, L89V I13V, K20T, E34EQ, N37C, R41RK, Q61QH, I62IV, L63P, I66V, A71T, I93L, C95CF  
>HIV270p| codons 1-99
PQITLWQRPFVTVKIGGQLTEALLDTGADDTVVQEMCLPGKWKPKMIGGIGGFIKVRQYD
HVPIEVCGHKTIGTVLVGPTPVNVIGRNVMTQLGFTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Y115F, Q151M, M184V A62V, K70S, V75I, F77L, F116Y L100I, K103N   I31R, V35I, T58N, I142V, T165I, T200E, I202V, R211K, L228R, V245VE, D250E, K277R, L283I, T286A, I293V, Q334L  
>HIV270p| codons 1-339
PISPIETVPVKLKPGMDGPKVKQWPLTEEKRKALIEICTEMEKEGKISKIGPENPYNNPV
FVIKKKDSTSWRKLIDLRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAFYSVPL
DKDFRKYTAFTIPSINNETPGVRYQYNVLPMGWKGSPAIFQSSMIKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHREKVEELRQHLLKWGFTTPDKKHQKEPPFRWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLIRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLGQWTY

References
Author Title Citation
Rangel, HR Absence of primary integrase resistance mutations in HIV type 1-infected patients in Venezuela. ARHR, 2010