<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84IV, L90M L10LF, V32VL, L89V I13V, K20KT, L33V, E34EQ, N37C, R41RK, Q61QH, I62IV, L63P, I66IV, A71AT, I93IL, C95CF F99FC
>HIV270b| codons 1-99
PQITLWQRPFVTVKIGGQLTEALLDTGADDTLVQEMCLPGKWKPKMIGGIGGFIKVRQYD
HVPIEVCGHKTIGTVLVGPTPVNVIGRNVMTQLGFTLNC

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KNRS, Y115F, Q151M, M184V A62AV, V75I, F77L, F116Y L100I, K103N   I31IR, V35I, T58TN, R83RK, I142V, T165I, T200E, I202V, R211K, L228R, D250E, K277R, L283I, T286A, I293IV, Q334L  
>HIV270b| codons 1-342
PISPIETVPVKLKPGMDGPKVKQWPLTEEKRKALIEICTEMEKEGKISKIGPENPYNNPV
FVIKKKDSTSWRKLIDLRELNKKTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAFYSVPL
DKDFRKYTAFTIPSINNETPGVRYQYNVLPMGWKGSPAIFQSSMIKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHREKVEELRQHLLKWGFTTPDKKHQKEPPFRWMGYELHPDKWT
VQPIVLPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLIRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLGQWTYQIY

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    A23V, L101I, K103KR, M154L, T218S, D253E  
>HIV270b| codons 22-288
MVSDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKIILVAVHVAS
GYIEAEVIPAETGQETAYFILRLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGI
PYNPQSQGVVESLNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIV
DIIATDIQTKELQKQISKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQENSDIKVVP
RRKAKIIRDYGKQMAGDDCVASRQDED

References
Author Title Citation
Rangel, HR Absence of primary integrase resistance mutations in HIV type 1-infected patients in Venezuela. ARHR, 2010