<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N N88D L10I, I13V, K20R, E35D, M36I, R57K, I62V, L63C, I64MV, I66F, A71V, I72V  
>HIV247p| codons 1-99
PQITLWQRPIVTVKIGGQLREALLDTGADNTVLEDINLPGRWKPKMIGGIGGFIKVKQYD
QVCVEFCGHKVVGTVLVGPTPVNIIGRDLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V   L100I, K103N   T69N, D177N, V179VI, G196E, V245Q, K275Q, V276T, K281R, A288S, V292VI, E297A, D324E, Q334H  
>HIV247p| codons 1-339
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSNKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNIII
YQYMDDLYVGSDLEIEQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIQTKQLCRLLRGTKSLTEIIPLTAEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGHGQWTY

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    Q53H, I72V, P90S, L101I, T112I, T124A, E157Q, K160Q  
>HIV247p| codons 22-288
MASDFNLPPVVAKEIVASCDKCQLKGEAMHGHVDCSPGIWQLDCTHLEGKVILVAVHVAS
GYIEAEVISAETGQETAYFILKLAGRWPVKIIHTDNGSNFTSATVKAACWWAGIKQEFGI
PYNPQSQGVVESMNKQLKQIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIV
DIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVP
RRKAKIIRDYGKQMAGDDCVASRQDED

References
Author Title Citation
Rangel, HR Absence of primary integrase resistance mutations in HIV type 1-infected patients in Venezuela. ARHR, 2010