Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5173 | CA16984 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 69 |
| 2 | 3TC+AZT+NFV | 43 |
| 3 | D4T+RTV+SQV | 44 |
| 4 | DDI+IDV+RTV | 52 |
| 5 | 3TC+APV+EFV | 24 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46L, I54V, L90M | L33IM, N88D | I13V, E35D, M36I, N37NI, L38LF, K43KN, R57K, L63P, A71T, I93L | T26TP |
| >CA16984| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDPGADNTVIEDIIFPGRWNPKLIGGIGGFVKVKQYD QIPIEICGHKTIGTVLVGPTPVNIIGRDLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, L210W, T215Y | G190Q | E6D, K43E, V118I, Q174H, Q207E, R211K, L228HR, A272P, E297K |
| >CA16876| codons 1-303 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKHNPDIVI YQYMDDLYVQSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTKEAE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |