<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16E, L19I, M36I, R41K, L63T, H69K, I93L  
>VL07_109| codons 1-99
PQITLWQRPLVSIKVEGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QITIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y   Y181C   K32E, V35T, E36A, T39D, S48T, V60I, V108X, D121H, K122E, I135R, T139R, S162A, K173A, Q174K, D177E, G196E, T200A, E203K, Q207G, R211K, H221Y, V245E, A272P, K275R, E291D, V292I, I293V  
>VL07_109| codons 1-300
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIEALTAICDELEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTLLDVGDAYFSVPL
HEDFRKYTAFTIPSRNNERPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI
CQYVDDLYVGSDLEIEQHRAKIKELRGHLLKWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTDIVPLTEEAE

References
Author Title Citation
Kandathil, AJ A comparison of interpretation by three different HIV type 1 genotypic drug resistance algorithms using sequences from non-clade B HIV type 1 strains. ARHR, 2009