<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  T97A L101I, T112I, T124A, T125V, K136Q, V201I, T218S, Y227F, L234V, S255N, D256E, V260I S283G
>95cmmp257| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQEAAYFILKLAGRWPVKIIHTDNGSN
FTSAVVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQISKIQNFRVYFRDSRDPVWKGPAK
LLWKGEGAVVIQDNNEIKVIPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I15V, K20R, E35D, M36I, R41K, I62V, L63S, H69Q, L89M  
>95cmmp257| codons 1-99
PQITLWQRPVVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVSIEICGQKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K104R, D123E, T165I, Q174E, D177E, T200A, Q207E, P243A, V245Q, E248D, D250S, A272P, K275R, Q278H, E291D, I293V, E297A, Q334H, G335D, F346H, M357R, R358K, G359S, A371V, I375V, S379G, T386V, K390R, A400I, K431T, V435I, V458I, D471E, H483Q, L491S, Q509H, L517I, S519N, K527Q, K530R, A534S, A554T  
>95cmmp257| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKENPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQAIQLPDKSSWTVNDIQKLVGKLNWASQIYPGIRVKHLCKLLRGTKALTDVVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPHKNLKTGKYARRKSA
HTNDVKQLTEVVQKVATEGIVIWGKVPKFRLPIQKETWEIWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIIGAETFYVDGAANRETKLGKAGYITDRGRQKVVSLTETTNQKTELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAHPDKSESEIVNQIIEQLIQKERVYLSWVPAHK
GIGGNEQVDKLVSTGIRKVL

References
Author Title Citation
Triques, K Near full length genome sequencing of divergent African HIV type 1 subtype F viruses leads to identification of a new HIV type 1 designated K. ARHR, 2000