<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, K20V, E35D, M36I, R41K, K43R, H69K, L89M  
>VI2642| codons 10-99
LVTVKVGGQLVEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVRQYDQILIEICGK
KAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36D, D123E, I135V, S162A, K173T, Q174E, D177E, T200A, Q207E, R211T, V245Q, E248G, Q278N, T286A, E291D, V292I, I293V, P294T, S322T  
>VI2642| codons 1-323
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLTWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPGKDSWTVNDIQKLVGKLNWASQIYAGIKVKNLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTK

References
Author Title Citation
Arien, KK Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time. AIDS, 2005