<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V82I, L89M, I93V  
>96CMABB55| codons 1-99
PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQVGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40D, K49R, V60I, A98S, K173A, Q174K, D177E, T200A, Q207K, R211S, V245Q, D250E, A272P, K281R, T286A, E291D, V292I, I293V, E297A, P321S, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, E370D, A371V, A376C, K390R, Q394R, A400V, E404D, Q428R, K431T, V435P, A437T, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L491S, K512R, S515A, L517V, S519N, A534S, A554S  
>96CMABB55| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDSSKELIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTDVVQKICTESIVIWGKTPKFRLPIRKETWEVWWTDYWQATWIPEWEFVNTP
PLVKLWYRLETEPIPGTETYYVDGAANRETKLGKAGYVTDKGKQKIITLTETTNQKAELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSEAEVVNQIIEQLIKKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V31I, L45V, M50I, T124G, T125A, G134N, K136T, Q164K, V201I, T206S, Y227F, L234I, S255N, D256E S283G
>96CMABB55| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQVKGEAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSGAVKAACWWANITQEFGIPYNPQSQGVVESMNKELKKIIGKVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYFRDSRDPIWKGPAK
LLWKGEGAVVIQDNNEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Holzmayer, V Near-full-length genomic sequence of a human immunodeficiency type 1 subtype g strain from Cameroon. ARHR, 2005