<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
A13458 A13458RS Cambodia 2006 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, M36I, N37T, R41K, K43R, L63P, H69K, K70KR, L89M  
>A13458RS| codons 4-99
TLWQRPLVTVKIGGQLIEALLDTGADDTVLEEITLPGKWRPKMIGGIGGFIKVRQYDQIP
IEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215TFIS   Y181C   K49KR, S68G, K101KR, I135V, S162AT, K173T, Q174R, D177E, I178M, T200TA, Q207DE, L210LM, H221Y, P243T, V245Q  
>A13458RS| codons 38-247
CTEMEKEGKISRIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLRKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQTSMTKILEPFRTRNPEMVICQYVDDLYVGSDLEIGQHRAKIEELREHLMRWGFSTP
DKKYQKEPPFLWMGYELHPDKWTVQTIQLP

References
Author Title Citation
Zolfo, M Genotypic impact of prolonged detectable HIV type 1 RNA viral load after HAART failure in a CRF01_AE-infected cohort. ARHR, 2010