<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
A15442 A15442M6 Cambodia 2006 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70KR, M184V D67DG, V75T, K219E Y181C V108I T39K, V60I, S68G, K102R, V106I, K122E, D123S, I135T, S162C, K173A, Q174K, D177E, V179I, T200I, Q207A, R211S, F214L, H221Y, K238R, V245E  
>A15442M6| codons 38-247
CKELEKEGKISKIGPENPYNTPIFAIKKKGGTRWRKLTDFRELNKRTQDFWEVQLGIPHP
AGLKRKKSITILDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRAKNPEIIICQYVDDLYVGSDLEIGQHRIKIEELRAHLLSWGLTTP
DEKYQKEPPFLWMGYELHPDRWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, E35D, M36I, R41K, L63C, H69K, K70R, L89M  
>A15442M6| codons 4-99
TLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIC
IEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Zolfo, M Genotypic impact of prolonged detectable HIV type 1 RNA viral load after HAART failure in a CRF01_AE-infected cohort. ARHR, 2010