<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, K70R, V75M, Q151M F77L, K219KE Y181C   T39E, S68G, K102KR, K103R, K122KE, D123S, I135IT, A158S, R172K, K173I, Q174K, D177E, I178M, Q207A, R211N, F214L, L228R, K238R, V245E P157A
>A 15293 BL| codons 38-247
CEEMEKEGKISKIGPENPYNTPVFAIKRKDGTRWRKLMDLRELNKRTQDFWEVQLGIPHP
AGLKRRKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSA
SIFQSSMTKILEPFKIKNPEMVICQYMDDLYVGSDLEIGQHRTKIEELRAHLLNWGLTTP
DEKHQKEPPFRWMGYELHPDRWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35ED, M36I, R41K, L63LV, H69K, L89M  
>A 15293 BL| codons 4-99
TLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIV
IEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Zolfo, M Genotypic impact of prolonged detectable HIV type 1 RNA viral load after HAART failure in a CRF01_AE-infected cohort. ARHR, 2010