<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SA-110206d SA-110206d U.S. 1996 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 67
2 AZT+DDI 155
3 AZT+DDC+DDI 62
4 AZT+DDC 56
5 AZT+DDC+SQV 89
6 3TC+AZT+SQV 37

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   L10V, K20KM, M36MI, D60E, L63LP, I64V  
>SA-110206d| codons 1-99
PQITLWQRPVVTIKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYE
QIPVEICGHKAIGTVLVGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Sevin, AD Methods for investigating the relationship between drug-susceptibility phenotype and HIV-1 genotype with applications to ACTG 333. J Infect Dis, 2000
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005