<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SA-240766d SA-240766d U.S. 1996 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 188
2 AZT+DDC+SQV 87
3 AZT+SQV 38
4 3TC+AZT+SQV 54

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84V, L90LM   L10I, N37D, K43R, I62V, L63PS, I64X, A71V, V77I, Q92R  
>SA-240766d| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMDLPGRWRPKMIGGIGGFIKVRQYD
QVPXEICGHKVIGTVLIGPTPVNVIGRNLMTRIGCTLNF

References
Author Title Citation
Sevin, AD Methods for investigating the relationship between drug-susceptibility phenotype and HIV-1 genotype with applications to ACTG 333. J Infect Dis, 2000
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005