<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
25-0446 25-0446 Thailand 2007 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M, M184V F77L, F116Y Y181C V108I T39K, K43E, S68G, D123N, K173I, Q174K, D177E, I178L, T200A, I202V, Q207E, R211K, H221Y, V245E  
>25-0446| codons 38-247
CKEMEEEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDLRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTILDVGDAYYSVPLDKNFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRIKNPELVICQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGFTTP
DKKYQKEPPFLWMGYELHPDKWTVQPIELP

References
Author Title Citation
Manosuthi, W Patients infected with HIV type 1 subtype CRF01_AE and failing first-line nevirapine- and efavirenz-based regimens demonstrate considerable cross-resistance to etravirine. ARHR, 2010