<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    S17N, S57G, T124N, T125A, Q137H, G163E, V165I, V201I, I203M, T218I, L234V, D256E S283G
>BREPM1026| codons 1-288
FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCGPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSNAVKAACWWAGIKHEFGIPYNPQSQGVVESMNKELKKIIEQIRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQIIKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, K14R, I15V, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, I62V, L63S, E65D, V77I, L89M, I93L  
>BREPM1026| codons 1-99
PQITLWQRPVVTIRVGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYE
NVSIDICGHKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40D, D123E, I135T, S162C, E169D, K173A, Q174K, D177E, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297V, V317A, D324E, Q334L, F346L, G359S, T377L, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, L452K, V466A, S468P, T470D, D471E, T477A, Q480E, H483Q, L491S, K512R, S519N, K527R, A534S, V559I  
>BREPM1026| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTVEAE
LELAENREILKEPVHGAYYDPSKELIAEIQKQGLGQWTYQIYQEPLKNLKTGKYARMRSA
HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPILKETWDTWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIAGAETFYVDGASNRETKKGKAGYVTDRGRQKAVPLDETTNQKAELE
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIRKEKVYLSWVPAHK
GIGGNEQVDKLVSAGIRKIL

References
Author Title Citation
Sa-Filho, D Characterization of the full-length human immunodeficiency virus-1 genome from recently infected subjects in Brazil. ARHR, 2007