<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63S  
>BREPM1029| codons 1-99
PQITLWQRPVVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NISIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39N, K49R, K104R, D123E, I135V, S162C, E169D, K173A, Q174K, D177E, T200A, Q207N, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297T, I329L, R356K, R358K, G359S, T377Q, Q394L, A400T, K431T, V435A, A446S, L452K, V466I, S468P, D471E, T477A, H483Q, I505V, K512R, L517I, S519N, K530R, A534S, V559I  
>BREPM1029| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRNHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYAKMKSA
HTNDVKQLTEAVQKIAQESIVIWGKTPKFKLPILKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIAGAETFYVDGASNRETKKGKAGYVTDRGRQKIVPLTETTNQKAELQ
AIQLALQDSGLEVNIVTDSQYALGVIQAQPDRSESEIVNQIIEQLIKKERVYLSWVPAHK
GIGGNEQVDKLVSAGIRKIL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, S17T, V37I, I72V, I84L, L101I, T112A, S119R, M154L, V165I, V201I, L234V, D256E  
>BREPM1029| codons 1-288
FLDGIDKAQEDHEKYHTNWRAMASDFNLPPVVAKEIIASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYLEAEVIPAETGQETAYFILKLAGRWPVKAIHTDNGRN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESLNKELKKIIGQIRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

References
Author Title Citation
Sa-Filho, D Characterization of the full-length human immunodeficiency virus-1 genome from recently infected subjects in Brazil. ARHR, 2007