Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4285 | CA16499 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 165 |
| 2 | 3TC+AZT | 59 |
| 3 | D4T+DDI+IDV | 97 |
| 4 | D4T+DDI+IDV+RTV | 53 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L | N37NT, R57K, D60E, Q61E, L63P, V77I, I85IV, I93L |
| >CA16499| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMTLPGRWKPKLIGGIGGFIKVKQYE EIPIEICGHKAIGTVLIGPTPVNIVGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215Y | M16L, K20R, I135V, S162C, T200A, E203ED, R211Q, T286A, I293V, E297A |
| >CA16420| codons 1-302 PISPIETVPVKLKPGLDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIDELRQHLLQWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTAEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |