<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA4409 CA16498 U.S. 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 79
2 AZT+DDI 31
3 3TC+AZT+IDV 74
4 APV+D4T+NVP 9
5 DDI+RTV+SQV 27
6 3TC+D4T 30
7 3TC+ABC+D4T 18
8 Unknown 46

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LI, I13V, K14KR, I15V, I62V, I64V, I72V, V77I  
>CA16498| codons 1-99
PQITLWQRPIVTVRVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVLVEICGHKAVGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, L210LW       K64KR, K122E, D123E, I135T, S162Y, N175NY, T200E, R211K, F214FL, T215X, T286A, A288AT, I293V, E297K A299AG
>CA16419| codons 1-303
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQYPDIVI
YQYMDDLYVGSDLEIGQHREKIEELRQHLWKWGLXTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKTLTEVVPLTKEGE
LEL

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005