<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI | RTI NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  G163K S17N, S39N, I72V, E96D, L101I, S119T, T124A, T125A, I135V, K136N, G193D, V201I, A205S, K211R, T218I, L234V, D256E, I268L, D270H S283G
>07BR_FPS783| codons 1-288
FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVANCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQDTAYFILKLAGRWPVKTIHTDNGTN
FTSAAVKAACWWAGVNQEFGIPYNPQSQGVVESMNKELKKIIKQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGDYSAGERIIDIISTDIQTRELQKQIIKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKILRHYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, E35D, M36I, R41K, R57K, Q61N, L89M, I93L  
>07BR_FPS783| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NILIEICGHKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K20R, V35T, T39E, K122E, I135V, S162C, K166R, E169D, K173A, Q174K, T200A, Q207A, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294S, E297V, V317A, D324E, R356K, G359S, T377L, Q394L, E399D, A400T, W402T, K431T, V435A, A446S, K451R, L452K, V467A, D471E, T477S, H483Q, L491S, S519N, A534S, V559I  
>07BR_FPS783| codons 1-560
PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTRILDPFRAKNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVSLTVEAE
LELAENREILKEPVHGAYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEAVQKIALESIVIWGKTPKFKLPILKETWDTWTTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIAGAETFYVDGASNRETRKGKAGYVTDRGRQKVASLTETTNQKSELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK
GIGGNEQVDKLVSAGIRKIL

References
Author Title Citation
Sanabani, SS Characterization and frequency of a newly identified HIV-1 BF1 intersubtype circulating recombinant form in Sao Paulo, Brazil. Virology J, 2010