<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, K14R, I15V, G16E, L19I, E35D, M36I, N37D, R41K, K45R, D60E, Q61E, L63S, H69K, L89I, I93L  
>07ZA17503| codons 1-99
PQITLWQRPLVAIRVEGQIKEALLDTGADDTVLEDIDLPGKWKPRMIGGIGGFIKVRQYE
EISIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        P4S, K20R, V35T, E36A, T39E, S48T, V60I, V118I, K122E, D123S, E138A, T165I, E169D, K173A, Q174K, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V  
>07ZA17503| codons 1-304
PISSIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMIKILDPFRAKNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    M50MI, L101I, T112V, T124A, I135IV, K136HQ, F181L, K188R, V201I, K211R, T218I, L234I, A265V, R269K, D278A S283G
>07ZA17503| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSATVKAACWWAGVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
LIHNFKRRGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED

References
Author Title Citation
Papathanasopoulos, MA Characterization of HIV type 1 genetic diversity among South African participants enrolled in the AIDS vaccine integrated project (AVIP) study. ARHR, 2010