<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67DN, K70KR, M184V, T215TFIS K219KQ Y181C V108VI K20KR, V21I, V35T, T39A, K82KR, I135T, K173T, Q174KR, D177E, T200E, Q207D, R211K, F214L, D218E, V245Q, E248D, D250E, K275Q, K277R, T286A, E291D, I293V, P294T, E312K, S322L, I326V  
>ZZR438| codons 1-334
PISPIETVPVKLKPGMDGPRIKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNRRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPEIVI
CQYVDDLYVGSDLEIGQHREKIEELRDHLLKWGLSTPEQKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYAGIQVRQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKKPVHGVYYDPLKDLVAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20R, E35D, M36I, R41K, H69K, L89M  
>ZZR438| codons 1-99
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009