<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR, M184V D67G, K219KE V106A A98G K20R, V35T, V60VI, S68G, D121H, K122E, I135L, K173T, Q174R, D177E, I178L, T200A, Q207E, F214L, V245Q, E248D, D250K, S251D, A272P, K277R, Q278H, K281R, T286A, V292I, I293V, E297A, L301M, P321S, S322E, D324E, E328D, I329V S105V
>ZZR472| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKGGTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKVATVLDVGDAYFSVPL
HEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPELVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDEKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKKDWTVNDIQKLVGKLNWASQIYPGIKVRHLCRLLRGAKALTEIVPLTAEAE
MELAENREILKEPVHGVYYDSEKELIADVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35D, M36I, R41K, C67S, H69K, V82I, L89M  
>ZZR472| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009