<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|TDF|D4T|AZT|NVP|EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215TNSY   K101EQ, Y181C, G190A V108I V21I, V35T, V60I, K122E, D123N, I135T, K173L, Q174R, D177E, T200A, Q207E, R211K, H221Y, V245Q, E248D, D250E, S251N, A272P, K275R, K277R, T286A, E291D, V292I, I293V G273N
>ZZR237| codons 1-333
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTILDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLRNPEIVI
CQYVDDLYVASDLEIGQHRAKIEELREHLLKWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPDKENWTVNDIQKLVGKLNWASQIYPNIRVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12N, I13V, K14R, L19I, K20I, E35Q, M36I, R41K, K45KR, R57K, L63LP, C67E, H69K, V82I, L89M  
>ZZR237| codons 1-99
PQITLWQRPLVNVRIGGQIIEALLDTGADDTVLEQINLPGKWKPRMIGGIGGFIKVKQYD
QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009