<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|NVP|EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, M184V K219Q K103N, Y181C, G190A A98G, V108I V35T, E36D, V60I, T69N, V106VI, D123E, I135V, S162A, K173A, Q174R, D177E, I178M, V179I, T200A, Q207E, R211K, F214L, H221Y, L228R, V245Q, A272P, K275R, K277R, T286A, E291D, V292I, I293V, P294T, S322T  
>ZZR236| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTELEKEGKISKIGPENPYNTPI
FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSITILDVGDAYFSVPL
DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRARNPEMII
CQYVDDLYVASDLEIGQHRAKIEELREHLLKWGLTTPDQKYQKEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12S, I13A, K14R, K20I, E35D, M36I, R41K, L63T, H69K, L89M  
>ZZR236| codons 1-99
PQITLWQRPVVSARIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009