Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| R234 | ZZR234 | Nigeria | 2007 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, K70R, M184V | K219Q | K103N | A98AG, K238T | V35T, K49R, V60I, V90I, D123E, I135V, S162A, E169R, K173T, Q174E, D177E, T200A, E203EK, Q207E, R211K, V245Q, S251SN, K275KR, T286A, E291D, V292I, I293V, P294T, S322A | R172T |
| >ZZR234| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILRPFTTENPEIVI YQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGFTTPDQKHQKEPPFLWMGYELHPDTWT VQPIQLPEKDNWTVNDIQKLVGKLNWASQIYAGIRVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G17E, K20I, M36I, N37D, R41K, L63PT, I64L, H69K, L89M |
| >ZZR234| codons 1-99 PQITLWQRPLVTVKIGEQLIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QITLEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Hawkins, CA | Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. | JAIDS, 2009 |