<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+TDF+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Y115F, M184V   K101E, Y181C, G190A   P4L, V35T, V60I, K104KR, V106I, D123S, K173V, Q174K, D177E, T200A, I202V, R211K, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294T, I326V  
>ZZR361| codons 1-333
PISLIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKRSITVLDVGDAFFSVPL
DKSFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPEIVI
CQYVDDLYVASDLEIGQHRAKVEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33IV, Q58E L10I, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89M  
>ZZR361| codons 1-99
PQITLWQRPIVTVRIGGQLIEALLDTGADDTVVEQIDLPGKWKPKMIGGIGGFIKVKEYD
QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009