<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70R, M184V, T215TFIS   Y181C, G190A A98AG, K101H P4S, V35T, D123E, I135V, S162A, K173T, Q174E, D177E, T200A, E204K, Q207E, R211K, F214L, K219G, H221Y, P243T, V245Q, A272P, K281KR, T286TA, E291D, V292VI, I293V, S322T, I326V  
>ZZR357| codons 1-334
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLHKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEIVI
CQYVDDLYVASDLEIGQHRAKIEKLREHLLKWGLSTPDGKYQKEPPFLWMGYELHPDKWT
VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G17E, K20I, M36I, N37S, R41K, L63P, G68GE, H69K, K70R, L89M  
>ZZR357| codons 1-99
PQITLWQRPLVTVKIGEQLIEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICEKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009