<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70KR, M184V T215TI K103N   K20R, V35T, E36ED, K46KQ, V60VI, A98AS, D121Y, K122E, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, E203EK, Q207E, R211K, P243A, V245Q, E248D, Q278N, L283I, T286A, E291D, V292I, I293V, P294T, S322T  
>ZZR356| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTDICTEMEKEGQISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI
YQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGFITPDKKHQKEPPFLWMGYELHPDKWT
VQAIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKNLCKLIRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11VI, L33F L10V, I13A, K20I, M36I, R41K, H69K, L89M  
>ZZR356| codons 1-99
PQITLWQRPVITAKIGGQLIEALLDTGADDTVFEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009