<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|D4T|NVP|EFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35D, M36I, R41K, R57K, L63Q, C67S, H69R, V77I, V82I, L89M  
>ZZR367| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QIQIEISGRKAIGTVLIGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y   K101E, Y181C, G190A A98G, V108VI K20R, E28K, K32KE, V35T, K49R, V60I, K104R, K122E, I135V, T139TI, K173IM, Q174K, D177E, T200A, Q207G, R211K, V241VI, V245Q, E248D, D250E, S251I, Q278H, T286A, E291D, V292I, I293V, E297T, L301M, I309IM, S322SA, I329V  
>ZZR367| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTKEKIEALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKKRSVTILDVGDAYFSVPL
DEDFRKYTAFTIPSVNNEIPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRMKNPEIVI
CQYVDDLYVASDLEIGQHRAKIEELRGHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
IQPIQLPDKEIWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGAKALTDIVPLTTEAE
MELAENREMLKEPVHGVYYDPAKDLIAEVQKQG

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009