<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|D4T|NVP|EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70R, M184V K219E Y181C, G190GA A98G V35T, T39L, V60I, W88C, K104R, V118VI, D121Y, K122E, D123DEKN, I135IT, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, S251D, A272P, K275R, T286A, E291D, V292I, I293V, E297K, E312G  
>ZZR366| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFCEVQLGIPHPGGLKKKRSVTVLDVGDAYFSIPL
YENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPELVI
CQYVDDLYVASDLEIGQHRAKIEELREHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKEDWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGAKALTDIVPLTKEAE
LELAENREILKGPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35Q, M36I, R41K, R57K, I64M, C67E, H69K, K70R, V82I, L89M  
>ZZR366| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD
QILMEIEGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009