Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|D4T|AZT|NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, M184V, T215FY | D67DE, V75VA | K103N | S3R, V35T, T39TA, E40ED, K49R, S68G, D123E, I135T, S162T, K173T, Q174K, D177E, I178M, T200A, E203ED, Q207A, R211K, V245Q, S251N, K275Q, T286A, E291D, V292I, I293V, P294T, L295M, E297EK, S322T, I326V |
| >ZZR255| codons 1-334 PIRPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICADLEKEGKISRIGPENPYNTPV FAIKKKEGTKWRKLADFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQTSMTKILEPFRTKNPEMVI YQYVDDLYVGSDLEIGQHRAKIDELRAHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDNWTVNDIQKLVGKLNWASQIYAGIQVKQLCKLLRGAKALTDIVTMTKEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20I, E35D, M36I, N37NS, R41K, H69K, L89M |
| >ZZR255| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Hawkins, CA | Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. | JAIDS, 2009 |